BDBM50132793 CHEMBL3634449
SMILES: COc1cc(ccc1NC(=O)c1occc1C)N1C(=O)c2ccccc2C1=O
InChI Key: InChIKey=JBQBAJBKVPMONK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50132793 (CHEMBL3634449) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 330 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Inhibition of bovine trypsin | Bioorg Med Chem Lett 25: 5107-10 (2015) BindingDB Entry DOI: 10.7270/Q20C4XKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50132793 (CHEMBL3634449) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 331 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGluR1 by calcium mobilization assay | Bioorg Med Chem Lett 25: 5107-10 (2015) BindingDB Entry DOI: 10.7270/Q20C4XKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human)) | BDBM50132793 (CHEMBL3634449) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay | Bioorg Med Chem Lett 25: 5107-10 (2015) BindingDB Entry DOI: 10.7270/Q20C4XKQ | |||||||||||
More data for this Ligand-Target Pair |