BDBM50133603 CHEMBL3633248
SMILES: COc1ccc(c(OC)c1)-c1cc(=O)[nH]c(=S)n1CC(N)=O
InChI Key: InChIKey=GQWZBUKEJKGQTB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Myeloperoxidase (MPO) (Homo sapiens (Human)) | BDBM50133603 (CHEMBL3633248) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 372 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of peroxidase activity of MPO isolated from human polynuclear leukocytes using Amplex Red as substrate assessed as formation of resorufin ... | J Med Chem 58: 8513-28 (2015) BindingDB Entry DOI: 10.7270/Q2SQ926X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (MPO) (Homo sapiens (Human)) | BDBM50133603 (CHEMBL3633248) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Irreversible inhibition of MPO in LPS-stimulated human whole blood after 4 hrs by Amplex Red/H2O2-based fluorescence plate reader analysis | J Med Chem 58: 8513-28 (2015) BindingDB Entry DOI: 10.7270/Q2SQ926X | |||||||||||
More data for this Ligand-Target Pair |