BDBM50133797 CHEMBL121743::N-[1-(1-Benzyl-piperidin-4-ylmethyl)-2-methyl-propyl]-4-methyl-benzamide

SMILES: CC(C)C(CC1CCN(Cc2ccccc2)CC1)NC(=O)c1ccc(C)cc1

InChI Key: InChIKey=JHASXLKKMOPARW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50133797 (CHEMBL121743 | N-[1-(1-Benzyl-piperidin-4-ylmethyl...) Show SMILES CC(C)C(CC1CCN(Cc2ccccc2)CC1)NC(=O)c1ccc(C)cc1 Show InChI InChI=1S/C25H34N2O/c1-19(2)24(26-25(28)23-11-9-20(3)10-12-23)17-21-13-15-27(16-14-21)18-22-7-5-4-6-8-22/h4-12,19,21,24H,13-18H2,1-3H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligand				Bioorg Med Chem Lett 13: 3597-600 (2003) BindingDB Entry DOI: 10.7270/Q228085J
					More data for this Ligand-Target Pair