BDBM50133918 5-(1,2,4,4a,5,6-Hexahydro-pyrazino[1,2-a]quinolin-3-yl)-1-phenyl-pentan-1-one::CHEMBL136961

SMILES: O=C(CCCCN1CCN2C(CCc3ccccc23)C1)c1ccccc1

InChI Key: InChIKey=SOOGRYSPVROLLT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50133918 (5-(1,2,4,4a,5,6-Hexahydro-pyrazino[1,2-a]quinolin-...) Show SMILES O=C(CCCCN1CCN2C(CCc3ccccc23)C1)c1ccccc1 Show InChI InChI=1S/C23H28N2O/c26-23(20-9-2-1-3-10-20)12-6-7-15-24-16-17-25-21(18-24)14-13-19-8-4-5-11-22(19)25/h1-5,8-11,21H,6-7,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	297	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Ability to compete with [3H]YM-09151-2 binding to the human dopamine receptor D3 transfected in CHO cells				J Med Chem 46: 4377-92 (2003) Article DOI: 10.1021/jm030085p BindingDB Entry DOI: 10.7270/Q21V5FPS
					More data for this Ligand-Target Pair