BDBM50134516 CHEMBL434637::Thiophene-2-sulfonic acid [3-(2''-benzyloxy-[1,1';3',1'']terphenyl-2-yl)-propionyl]-amide
SMILES: O=C(CCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1)NS(=O)(=O)c1cccs1
InChI Key: InChIKey=CPNNNLVYEXESBV-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50134516![]() (CHEMBL434637 | Thiophene-2-sulfonic acid [3-(2''-b...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50134516![]() (CHEMBL434637 | Thiophene-2-sulfonic acid [3-(2''-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50134516![]() (CHEMBL434637 | Thiophene-2-sulfonic acid [3-(2''-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50134516![]() (CHEMBL434637 | Thiophene-2-sulfonic acid [3-(2''-b...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair |