BDBM50134525 3-{2-[4-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl}-propionic acid::CHEMBL123855
SMILES: OC(=O)CCc1ccccc1-c1cc(cs1)-c1ccccc1OCc1ccccc1
InChI Key: InChIKey=CRYKVNWLVHWHOH-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50134525 (3-{2-[4-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50134525 (3-{2-[4-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50134525 (3-{2-[4-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM50134525 (3-{2-[4-(2-Benzyloxy-phenyl)-thiophen-2-yl]-phenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line. | Bioorg Med Chem Lett 13: 3813-6 (2003) BindingDB Entry DOI: 10.7270/Q26T0M1N | |||||||||||
More data for this Ligand-Target Pair |