BDBM50135292 1-(2-Chloro-phenyl)-6-(4-fluoro-phenylsulfanyl)-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::CHEMBL338612

SMILES: Fc1ccc(Sc2ccc3N(C(=O)NCc3n2)c2ccccc2Cl)cc1

InChI Key: InChIKey=WJKXYGGZKSIWQJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50135292 (1-(2-Chloro-phenyl)-6-(4-fluoro-phenylsulfanyl)-3,...) Show SMILES Fc1ccc(Sc2ccc3N(C(=O)NCc3n2)c2ccccc2Cl)cc1 Show InChI InChI=1S/C19H13ClFN3OS/c20-14-3-1-2-4-16(14)24-17-9-10-18(23-15(17)11-22-19(24)25)26-13-7-5-12(21)6-8-13/h1-10H,11H2,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 13: 3979-82 (2003) BindingDB Entry DOI: 10.7270/Q2RJ4HWB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50135292 (1-(2-Chloro-phenyl)-6-(4-fluoro-phenylsulfanyl)-3,...) Show SMILES Fc1ccc(Sc2ccc3N(C(=O)NCc3n2)c2ccccc2Cl)cc1 Show InChI InChI=1S/C19H13ClFN3OS/c20-14-3-1-2-4-16(14)24-17-9-10-18(23-15(17)11-22-19(24)25)26-13-7-5-12(21)6-8-13/h1-10H,11H2,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against mitogen-activated protein kinase p38 beta				Bioorg Med Chem Lett 13: 3979-82 (2003) BindingDB Entry DOI: 10.7270/Q2RJ4HWB
					More data for this Ligand-Target Pair