BDBM50135306 1-(2-Chloro-6-methyl-4-nitro-phenyl)-6-(4-fluoro-phenylsulfanyl)-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::CHEMBL127275

SMILES: Cc1cc(cc(Cl)c1N1C(=O)NCc2nc(Sc3ccc(F)cc3)ccc12)[N+]([O-])=O

InChI Key: InChIKey=CNKCXVOYRDHQSS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50135306 (1-(2-Chloro-6-methyl-4-nitro-phenyl)-6-(4-fluoro-p...) Show SMILES Cc1cc(cc(Cl)c1N1C(=O)NCc2nc(Sc3ccc(F)cc3)ccc12)[N+]([O-])=O Show InChI InChI=1S/C20H14ClFN4O3S/c1-11-8-13(26(28)29)9-15(21)19(11)25-17-6-7-18(24-16(17)10-23-20(25)27)30-14-4-2-12(22)3-5-14/h2-9H,10H2,1H3,(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 13: 3979-82 (2003) BindingDB Entry DOI: 10.7270/Q2RJ4HWB
					More data for this Ligand-Target Pair