BDBM50135314 1-(2,6-Dichloro-phenyl)-6-(2-fluoro-phenylsulfanyl)-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::CHEMBL340377

SMILES: Fc1ccccc1Sc1ccc2N(C(=O)NCc2n1)c1c(Cl)cccc1Cl

InChI Key: InChIKey=KSXXQEHURXYOHD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50135314 (1-(2,6-Dichloro-phenyl)-6-(2-fluoro-phenylsulfanyl...) Show SMILES Fc1ccccc1Sc1ccc2N(C(=O)NCc2n1)c1c(Cl)cccc1Cl Show InChI InChI=1S/C19H12Cl2FN3OS/c20-11-4-3-5-12(21)18(11)25-15-8-9-17(24-14(15)10-23-19(25)26)27-16-7-2-1-6-13(16)22/h1-9H,10H2,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 13: 3979-82 (2003) BindingDB Entry DOI: 10.7270/Q2RJ4HWB
					More data for this Ligand-Target Pair