BDBM50135592 2-(5-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-2-ene::CHEMBL96828

SMILES: C1CC2NC1CCC=C2c1cncc(c1)-c1ccccc1

InChI Key: InChIKey=DXMUMJDAIAZCTE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50135592 (2-(5-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...) Show SMILES C1CC2NC1CCC=C2c1cncc(c1)-c1ccccc1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C19H20N2/c1-2-5-14(6-3-1)15-11-16(13-20-12-15)18-8-4-7-17-9-10-19(18)21-17/h1-3,5-6,8,11-13,17,19,21H,4,7,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligand				Bioorg Med Chem Lett 13: 2825-8 (2003) BindingDB Entry DOI: 10.7270/Q2Z31Z26
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-3/beta-2 subunit (Homo sapiens (Human))	BDBM50135592 (2-(5-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...) Show SMILES C1CC2NC1CCC=C2c1cncc(c1)-c1ccccc1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C19H20N2/c1-2-5-14(6-3-1)15-11-16(13-20-12-15)18-8-4-7-17-9-10-19(18)21-17/h1-3,5-6,8,11-13,17,19,21H,4,7,9-10H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Binding affinity towards alpha3-beta4 subtype of neuronal nicotinic acetylcholine receptor (nAChR) using [3H]-epibatidine as radioligand				Bioorg Med Chem Lett 13: 2825-8 (2003) BindingDB Entry DOI: 10.7270/Q2Z31Z26
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50135592 (2-(5-Phenyl-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...) Show SMILES C1CC2NC1CCC=C2c1cncc(c1)-c1ccccc1 |c:8,THB:9:8:3:1.0| Show InChI InChI=1S/C19H20N2/c1-2-5-14(6-3-1)15-11-16(13-20-12-15)18-8-4-7-17-9-10-19(18)21-17/h1-3,5-6,8,11-13,17,19,21H,4,7,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Binding affinity towards Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligand				Bioorg Med Chem Lett 13: 2825-8 (2003) BindingDB Entry DOI: 10.7270/Q2Z31Z26
					More data for this Ligand-Target Pair