BDBM50135650 Benzo[b]thiophene-2-carboxylic acid (2-benzylsulfanyl-phenyl)-(4-dimethylamino-butyl)-amide::CHEMBL420630
SMILES: CN(C)CCCCN(C(=O)c1cc2ccccc2s1)c1ccccc1SCc1ccccc1
InChI Key: InChIKey=YPKZZQXDAZSUPY-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuropeptide Y receptor type 2 (Homo sapiens (Human)) | BDBM50135650![]() (Benzo[b]thiophene-2-carboxylic acid (2-benzylsulfa...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against SMS-KAN cell membranes endogenously expressing Neuropeptide Y receptor type 2 using [125I]-PYY as radioligand | Bioorg Med Chem Lett 13: 2883-5 (2003) BindingDB Entry DOI: 10.7270/Q2F47NJQ | |||||||||||
More data for this Ligand-Target Pair |