BDBM50135664 3-Morpholin-4-ylmethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-diamine::CHEMBL99776

SMILES: Nc1nc(N)c2nc(CN3CCOCC3)nnc2n1

InChI Key: InChIKey=KPNCDSYHEKUMBS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135664   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50135664 (3-Morpholin-4-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...) Show SMILES Nc1nc(N)c2nc(CN3CCOCC3)nnc2n1 Show InChI InChI=1S/C10H14N8O/c11-8-7-9(15-10(12)14-8)17-16-6(13-7)5-18-1-3-19-4-2-18/h1-5H2,(H4,11,12,14,15,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTT				Bioorg Med Chem Lett 13: 2895-8 (2003) BindingDB Entry DOI: 10.7270/Q21V5DDS
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50135664 (3-Morpholin-4-ylmethyl-pyrimido[5,4-e][1,2,4]triaz...) Show SMILES Nc1nc(N)c2nc(CN3CCOCC3)nnc2n1 Show InChI InChI=1S/C10H14N8O/c11-8-7-9(15-10(12)14-8)17-16-6(13-7)5-18-1-3-19-4-2-18/h1-5H2,(H4,11,12,14,15,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Inhibition of Protein-tyrosine phosphatase 1B in 2 mM DTT				Bioorg Med Chem Lett 13: 2895-8 (2003) BindingDB Entry DOI: 10.7270/Q21V5DDS
					More data for this Ligand-Target Pair