BDBM50136011 9-(1-ethoxyethyl)-12-(3-hydroxypropyl)-6,7,12,13-tetrahydro-5H-indeno[2,1-a]pyrrolo[4,3-c]carbazol-5-one::CHEMBL359316

SMILES: CCOC(C)c1ccc2n(CCCO)c3c4Cc5ccccc5-c4c4C(=O)NCc4c3c2c1

InChI Key: InChIKey=ZGDQUQUBRNXFSB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50136011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50136011 (9-(1-ethoxyethyl)-12-(3-hydroxypropyl)-6,7,12,13-t...) Show SMILES CCOC(C)c1ccc2n(CCCO)c3c4Cc5ccccc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C28H28N2O3/c1-3-33-16(2)17-9-10-23-20(13-17)25-22-15-29-28(32)26(22)24-19-8-5-4-7-18(19)14-21(24)27(25)30(23)11-6-12-31/h4-5,7-10,13,16,31H,3,6,11-12,14-15H2,1-2H3,(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc Curated by ChEMBL					Assay Description Inhibition of human Vascular endothelial growth factor receptor 2				J Med Chem 46: 5375-88 (2003) Article DOI: 10.1021/jm0301641 BindingDB Entry DOI: 10.7270/Q2V69J1X
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50136011 (9-(1-ethoxyethyl)-12-(3-hydroxypropyl)-6,7,12,13-t...) Show SMILES CCOC(C)c1ccc2n(CCCO)c3c4Cc5ccccc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C28H28N2O3/c1-3-33-16(2)17-9-10-23-20(13-17)25-22-15-29-28(32)26(22)24-19-8-5-4-7-18(19)14-21(24)27(25)30(23)11-6-12-31/h4-5,7-10,13,16,31H,3,6,11-12,14-15H2,1-2H3,(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc Curated by ChEMBL					Assay Description In vitro inhibitory concentration against human vascular endothelial growth factor receptor 2				J Med Chem 46: 5375-88 (2003) Article DOI: 10.1021/jm0301641 BindingDB Entry DOI: 10.7270/Q2V69J1X
					More data for this Ligand-Target Pair