BindingDB logo
myBDB logout

null

SMILES: COCC(=O)NCCC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1

InChI Key: InChIKey=KGDZBOMXHSDSOS-RUZDIDTESA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136356   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50136356
PNG
(CHEMBL343742 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Show SMILES COCC(=O)NCCC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1
Show InChI InChI=1S/C29H41ClN6O4/c1-40-18-27(38)32-14-11-26(37)34-25(17-22-7-9-24(30)10-8-22)28(39)35-15-12-29(13-16-35,19-36-21-31-20-33-36)23-5-3-2-4-6-23/h7-10,20-21,23,25H,2-6,11-19H2,1H3,(H,32,38)(H,34,37)/t25-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 21n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptors

Bioorg Med Chem Lett 13: 4341-4 (2003)


BindingDB Entry DOI: 10.7270/Q2F18Z4D
More data for this
Ligand-Target Pair