BDBM50136361 (R)-Piperidine-3-carboxylic acid {2-[(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethylcarbamoyl]-ethyl}-amide::CHEMBL344231

SMILES: Clc1ccc(C[C@@H](NC(=O)CCNC(=O)[C@@H]2CCCNC2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1

InChI Key: InChIKey=PYZNQWVWNZMBOX-LEAFIULHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50136361 ((R)-Piperidine-3-carboxylic acid {2-[(R)-1-(4-chlo...) Show SMILES Clc1ccc(C[C@@H](NC(=O)CCNC(=O)[C@@H]2CCCNC2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1 Show InChI InChI=1S/C32H46ClN7O3/c33-27-10-8-24(9-11-27)19-28(38-29(41)12-16-36-30(42)25-5-4-15-34-20-25)31(43)39-17-13-32(14-18-39,21-40-23-35-22-37-40)26-6-2-1-3-7-26/h8-11,22-23,25-26,28,34H,1-7,12-21H2,(H,36,42)(H,38,41)/t25-,28-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptors				Bioorg Med Chem Lett 13: 4341-4 (2003) BindingDB Entry DOI: 10.7270/Q2F18Z4D
					More data for this Ligand-Target Pair