BDBM50136364 (R)-Piperidine-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide::CHEMBL435400

SMILES: Clc1ccc(C[C@@H](NC(=O)[C@@H]2CCCNC2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1

InChI Key: InChIKey=SZMRJYQXIMNTTB-ZEQKJWHPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50136364 ((R)-Piperidine-3-carboxylic acid [(R)-1-(4-chloro-...) Show SMILES Clc1ccc(C[C@@H](NC(=O)[C@@H]2CCCNC2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1 Show InChI InChI=1S/C29H41ClN6O2/c30-25-10-8-22(9-11-25)17-26(34-27(37)23-5-4-14-31-18-23)28(38)35-15-12-29(13-16-35,19-36-21-32-20-33-36)24-6-2-1-3-7-24/h8-11,20-21,23-24,26,31H,1-7,12-19H2,(H,34,37)/t23-,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptors				Bioorg Med Chem Lett 13: 4341-4 (2003) BindingDB Entry DOI: 10.7270/Q2F18Z4D
					More data for this Ligand-Target Pair