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SMILES: Clc1ccc(C[C@@H](NC(=O)C2CNC2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1

InChI Key: InChIKey=KHNQSRNCDZKWEG-XMMPIXPASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136368   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50136368
PNG
(Azetidine-3-carboxylic acid [(R)-1-(4-chloro-benzy...)
Show SMILES Clc1ccc(C[C@@H](NC(=O)C2CNC2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1
Show InChI InChI=1S/C27H37ClN6O2/c28-23-8-6-20(7-9-23)14-24(32-25(35)21-15-29-16-21)26(36)33-12-10-27(11-13-33,17-34-19-30-18-31-34)22-4-2-1-3-5-22/h6-9,18-19,21-22,24,29H,1-5,10-17H2,(H,32,35)/t24-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 16n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptors

Bioorg Med Chem Lett 13: 4341-4 (2003)


BindingDB Entry DOI: 10.7270/Q2F18Z4D
More data for this
Ligand-Target Pair