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SMILES: Clc1ccc(C[C@@H](NC(=O)CCNC(=O)[C@H]2CCCNC2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1

InChI Key: InChIKey=PYZNQWVWNZMBOX-LBNVMWSVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136369   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50136369
PNG
((S)-Piperidine-3-carboxylic acid {2-[(R)-1-(4-chlo...)
Show SMILES Clc1ccc(C[C@@H](NC(=O)CCNC(=O)[C@H]2CCCNC2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1
Show InChI InChI=1S/C32H46ClN7O3/c33-27-10-8-24(9-11-27)19-28(38-29(41)12-16-36-30(42)25-5-4-15-34-20-25)31(43)39-17-13-32(14-18-39,21-40-23-35-22-37-40)26-6-2-1-3-7-26/h8-11,22-23,25-26,28,34H,1-7,12-21H2,(H,36,42)(H,38,41)/t25-,28+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 22n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptors

Bioorg Med Chem Lett 13: 4341-4 (2003)


BindingDB Entry DOI: 10.7270/Q2F18Z4D
More data for this
Ligand-Target Pair