BDBM50136907 CHEMBL153876::N-(3-Chloro-7-isobutylamino-1H-indazol-5-yl)-3-(2-methyl-pyrimidin-4-yl)-benzenesulfonamide
SMILES: CC(C)CNc1cc(NS(=O)(=O)c2cccc(c2)-c2ccnc(C)n2)cc2c(Cl)[nH]nc12
InChI Key: InChIKey=QZZSXZNREWWFSP-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12)) | BDBM50136907 (CHEMBL153876 | N-(3-Chloro-7-isobutylamino-1H-inda...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Quorex Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase) | J Med Chem 46: 5663-73 (2003) Article DOI: 10.1021/jm0302039 BindingDB Entry DOI: 10.7270/Q279443D | |||||||||||
More data for this Ligand-Target Pair |