BDBM50137132 3-[3-(3-Trifluoromethyl-phenyl)-ureido]-naphthalene-2-carboxylic acid::CHEMBL347828

SMILES: OC(=O)c1cc2ccccc2cc1NC(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=LCQIGIDPNWGZGO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIK1 (Homo sapiens (Human))	BDBM50137132 (3-[3-(3-Trifluoromethyl-phenyl)-ureido]-naphthalen...) Show SMILES OC(=O)c1cc2ccccc2cc1NC(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H13F3N2O3/c20-19(21,22)13-6-3-7-14(10-13)23-18(27)24-16-9-12-5-2-1-4-11(12)8-15(16)17(25)26/h1-10H,(H,25,26)(H2,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against human ionotropic glutamate receptor ionotropic kainate 1 (GluR-5) expressed in HEK293 cells.				J Med Chem 46: 5834-43 (2003) Article DOI: 10.1021/jm030428j BindingDB Entry DOI: 10.7270/Q2KK9B60
					More data for this Ligand-Target Pair