BDBM50137152 4-Chloro-2-(3-pyridin-2-yl-ureido)-benzoic acid::CHEMBL154678

SMILES: OC(=O)c1ccc(Cl)cc1NC(=O)Nc1ccccn1

InChI Key: InChIKey=LYJNLSVTXUEARX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIK1 (Homo sapiens (Human))	BDBM50137152 (4-Chloro-2-(3-pyridin-2-yl-ureido)-benzoic acid | ...) Show SMILES OC(=O)c1ccc(Cl)cc1NC(=O)Nc1ccccn1 Show InChI InChI=1S/C13H10ClN3O3/c14-8-4-5-9(12(18)19)10(7-8)16-13(20)17-11-3-1-2-6-15-11/h1-7H,(H,18,19)(H2,15,16,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against human ionotropic glutamate receptor ionotropic kainate 1 (GluR-5) expressed in HEK293 cells.				J Med Chem 46: 5834-43 (2003) Article DOI: 10.1021/jm030428j BindingDB Entry DOI: 10.7270/Q2KK9B60
					More data for this Ligand-Target Pair