BDBM50137189 4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidine-6-carboxylic acid propylamide::CHEMBL421329

SMILES: CCCNC(=O)c1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2s1

InChI Key: InChIKey=ZBMVTZKSSKNBMX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50137189 (4-(1H-Indol-5-ylamino)-thieno[3,2-d]pyrimidine-6-c...) Show SMILES CCCNC(=O)c1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2s1 Show InChI InChI=1S/C18H17N5OS/c1-2-6-20-18(24)15-9-14-16(25-15)17(22-10-21-14)23-12-3-4-13-11(8-12)5-7-19-13/h3-5,7-10,19H,2,6H2,1H3,(H,20,24)(H,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against Vascular endothelial growth factor receptor				Bioorg Med Chem Lett 14: 21-4 (2003) BindingDB Entry DOI: 10.7270/Q2FT8KFT
					More data for this Ligand-Target Pair