BDBM50137425 2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-(methylsulfonyl)pyridine::2-(3-Difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine::CHEMBL174219

SMILES: CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccccc1)C(F)F

InChI Key: InChIKey=LNEWNCVYPLKLFQ-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50137425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-1 (Canis familiaris)	BDBM50137425 (2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccccc1)C(F)F Show InChI InChI=1S/C16H13F2N3O2S/c1-24(22,23)12-7-8-15(19-10-12)21-14(9-13(20-21)16(17)18)11-5-3-2-4-6-11/h2-10,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (Canis familiaris)	BDBM50137425 (2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccccc1)C(F)F Show InChI InChI=1S/C16H13F2N3O2S/c1-24(22,23)12-7-8-15(19-10-12)21-14(9-13(20-21)16(17)18)11-5-3-2-4-6-11/h2-10,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Veterinary Medicine Research and Development Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against COX1 in canine whole blood				Bioorg Med Chem Lett 16: 288-92 (2005) Article DOI: 10.1016/j.bmcl.2005.10.006 BindingDB Entry DOI: 10.7270/Q2NZ876S
					More data for this Ligand-Target Pair
Cyclooxygenase-2 (Canis familiaris)	BDBM50137425 (2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccccc1)C(F)F Show InChI InChI=1S/C16H13F2N3O2S/c1-24(22,23)12-7-8-15(19-10-12)21-14(9-13(20-21)16(17)18)11-5-3-2-4-6-11/h2-10,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX2 by canine whole blood assay				Bioorg Med Chem Lett 16: 1202-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.110 BindingDB Entry DOI: 10.7270/Q2FT8KKM
					More data for this Ligand-Target Pair
Cyclooxygenase-2 (Canis familiaris)	BDBM50137425 (2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccccc1)C(F)F Show InChI InChI=1S/C16H13F2N3O2S/c1-24(22,23)12-7-8-15(19-10-12)21-14(9-13(20-21)16(17)18)11-5-3-2-4-6-11/h2-10,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Veterinary Medicine Research and Development Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against COX2 in canine whole blood				Bioorg Med Chem Lett 16: 288-92 (2005) Article DOI: 10.1016/j.bmcl.2005.10.006 BindingDB Entry DOI: 10.7270/Q2NZ876S
					More data for this Ligand-Target Pair
Cyclooxygenase-2 (Canis familiaris)	BDBM50137425 (2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...) Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccccc1)C(F)F Show InChI InChI=1S/C16H13F2N3O2S/c1-24(22,23)12-7-8-15(19-10-12)21-14(9-13(20-21)16(17)18)11-5-3-2-4-6-11/h2-10,16H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair