BDBM50137494 1-Cyclohexyl-2-(2,4,6-trimethyl-phenyl)-1H-benzoimidazole-5-carboxylic acid::CHEMBL178067

SMILES: Cc1cc(C)c(-c2nc3cc(ccc3n2C2CCCCC2)C(O)=O)c(C)c1

InChI Key: InChIKey=HAKZNWGRHQJUBQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50137494 (1-Cyclohexyl-2-(2,4,6-trimethyl-phenyl)-1H-benzoim...) Show SMILES Cc1cc(C)c(-c2nc3cc(ccc3n2C2CCCCC2)C(O)=O)c(C)c1 |(1.01,-2.08,;2.55,-2.08,;3.34,-3.41,;4.86,-3.41,;4.86,-4.95,;5.63,-2.1,;7.17,-2.11,;8.08,-.87,;9.54,-1.34,;10.87,-.57,;12.21,-1.34,;12.21,-2.88,;10.87,-3.65,;9.54,-2.88,;8.08,-3.36,;7.54,-4.79,;6.02,-5.05,;5.48,-6.49,;6.46,-7.68,;7.98,-7.43,;8.52,-5.98,;13.56,-.56,;14.89,-1.33,;13.54,.98,;4.88,-.75,;5.65,.58,;3.34,-.75,)| Show InChI InChI=1S/C23H26N2O2/c1-14-11-15(2)21(16(3)12-14)22-24-19-13-17(23(26)27)9-10-20(19)25(22)18-7-5-4-6-8-18/h9-13,18H,4-8H2,1-3H3,(H,26,27)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd Curated by ChEMBL					Assay Description Inhibitory activity against NS5B polymerase of hepatitis C virus				Bioorg Med Chem Lett 14: 119-24 (2003) BindingDB Entry DOI: 10.7270/Q21J9968
					More data for this Ligand-Target Pair