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BDBM50137495 1-Cyclohexyl-2-(6-methyl-pyridin-2-yl)-1H-benzoimidazole-5-carboxylic acid::CHEMBL367758

SMILES: Cc1cccc(n1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O

InChI Key: InChIKey=RJDGXOOOFPOIAC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137495   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)		BDBM50137495
PNG
(1-Cyclohexyl-2-(6-methyl-pyridin-2-yl)-1H-benzoimi...)
Show SMILES Cc1cccc(n1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Show InChI InChI=1S/C20H21N3O2/c1-13-6-5-9-16(21-13)19-22-17-12-14(20(24)25)10-11-18(17)23(19)15-7-3-2-4-8-15/h5-6,9-12,15H,2-4,7-8H2,1H3,(H,24,25)
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against NS5B polymerase of hepatitis C virus

Bioorg Med Chem Lett 14: 119-24 (2003)


BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair