BDBM50137986 3-Hydroxy-10-keto-N-(3-fluoropropyl)morphinan::CHEMBL295237

SMILES: Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCCF)c2c1

InChI Key: InChIKey=LDUCOIQQNZJWTI-VDZJLULYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50137986 (3-Hydroxy-10-keto-N-(3-fluoropropyl)morphinan | CH...) Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCCF)c2c1 Show InChI InChI=1S/C19H24FNO2/c20-9-3-10-21-11-8-19-7-2-1-4-15(19)17(21)18(23)14-6-5-13(22)12-16(14)19/h5-6,12,15,17,22H,1-4,7-11H2/t15-,17-,19+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.				J Med Chem 47: 165-74 (2003) Article DOI: 10.1021/jm0304156 BindingDB Entry DOI: 10.7270/Q2KD1XB2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50137986 (3-Hydroxy-10-keto-N-(3-fluoropropyl)morphinan | CH...) Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCCF)c2c1 Show InChI InChI=1S/C19H24FNO2/c20-9-3-10-21-11-8-19-7-2-1-4-15(19)17(21)18(23)14-6-5-13(22)12-16(14)19/h5-6,12,15,17,22H,1-4,7-11H2/t15-,17-,19+/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.				J Med Chem 47: 165-74 (2003) Article DOI: 10.1021/jm0304156 BindingDB Entry DOI: 10.7270/Q2KD1XB2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50137986 (3-Hydroxy-10-keto-N-(3-fluoropropyl)morphinan | CH...) Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCCF)c2c1 Show InChI InChI=1S/C19H24FNO2/c20-9-3-10-21-11-8-19-7-2-1-4-15(19)17(21)18(23)14-6-5-13(22)12-16(14)19/h5-6,12,15,17,22H,1-4,7-11H2/t15-,17-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.				J Med Chem 47: 165-74 (2003) Article DOI: 10.1021/jm0304156 BindingDB Entry DOI: 10.7270/Q2KD1XB2
					More data for this Ligand-Target Pair