BDBM50138070 (2-{2-[(R)-4-(6-Fluoro-hexyl)-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-2-yl]-ethoxy}-phenyl)-acetic acid::CHEMBL355586

SMILES: OC(=O)Cc1ccccc1OCC[C@H]1Oc2ccccc2N(CCCCCCF)C1=O

InChI Key: InChIKey=UALXBJPTYCHHJQ-JOCHJYFZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50138070 ((2-{2-[(R)-4-(6-Fluoro-hexyl)-3-oxo-3,4-dihydro-2H...) Show SMILES OC(=O)Cc1ccccc1OCC[C@H]1Oc2ccccc2N(CCCCCCF)C1=O Show InChI InChI=1S/C24H28FNO5/c25-14-7-1-2-8-15-26-19-10-4-6-12-21(19)31-22(24(26)29)13-16-30-20-11-5-3-9-18(20)17-23(27)28/h3-6,9-12,22H,1-2,7-8,13-17H2,(H,27,28)/t22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	152	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonistic activity against PPAR (peroxisome proliferator activated receptor gamma) in Suarus chinesis				J Med Chem 47: 196-209 (2003) Article DOI: 10.1021/jm0301888 BindingDB Entry DOI: 10.7270/Q29Z9495
					More data for this Ligand-Target Pair