BDBM50138077 6-{2-[2-(2-Carboxymethyl-phenoxy)-ethyl]-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl}-hexanoic acid::CHEMBL178064

SMILES: OC(=O)CCCCCN1C(=O)C(CCOc2ccccc2CC(O)=O)Oc2ccccc12

InChI Key: InChIKey=JXXWJYQMPBDFHC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50138077 (6-{2-[2-(2-Carboxymethyl-phenoxy)-ethyl]-3-oxo-2,3...) Show SMILES OC(=O)CCCCCN1C(=O)C(CCOc2ccccc2CC(O)=O)Oc2ccccc12 Show InChI InChI=1S/C24H27NO7/c26-22(27)12-2-1-7-14-25-18-9-4-6-11-20(18)32-21(24(25)30)13-15-31-19-10-5-3-8-17(19)16-23(28)29/h3-6,8-11,21H,1-2,7,12-16H2,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonistic activity against PPAR (peroxisome proliferator activated receptor gamma) in Suarus chinesis				J Med Chem 47: 196-209 (2003) Article DOI: 10.1021/jm0301888 BindingDB Entry DOI: 10.7270/Q29Z9495
					More data for this Ligand-Target Pair