BDBM50138080 CHEMBL176035::{2-[2-(3-Oxo-4-propylcarbamoylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-2-yl)-ethoxy]-phenyl}-acetic acid

SMILES: CCCNC(=O)CN1C(=O)C(CCOc2ccccc2CC(O)=O)Oc2ccccc12

InChI Key: InChIKey=UHXBMLCSHRNMIX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50138080 (CHEMBL176035 | {2-[2-(3-Oxo-4-propylcarbamoylmethy...) Show SMILES CCCNC(=O)CN1C(=O)C(CCOc2ccccc2CC(O)=O)Oc2ccccc12 Show InChI InChI=1S/C23H26N2O6/c1-2-12-24-21(26)15-25-17-8-4-6-10-19(17)31-20(23(25)29)11-13-30-18-9-5-3-7-16(18)14-22(27)28/h3-10,20H,2,11-15H2,1H3,(H,24,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonistic activity against PPAR (peroxisome proliferator activated receptor gamma) in Suarus chinesis				J Med Chem 47: 196-209 (2003) Article DOI: 10.1021/jm0301888 BindingDB Entry DOI: 10.7270/Q29Z9495
					More data for this Ligand-Target Pair