BDBM50138553 CHEMBL421793::N-(4-Phenyl-butyl)-2-{[2-(4-trifluoromethyl-phenyl)-ethylamino]-methyl}-benzamide

SMILES: FC(F)(F)c1ccc(CCNCc2ccccc2C(=O)NCCCCc2ccccc2)cc1

InChI Key: InChIKey=XZPRSDUDMGYTPI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50138553 (CHEMBL421793 | N-(4-Phenyl-butyl)-2-{[2-(4-trifluo...) Show SMILES FC(F)(F)c1ccc(CCNCc2ccccc2C(=O)NCCCCc2ccccc2)cc1 Show InChI InChI=1S/C27H29F3N2O/c28-27(29,30)24-15-13-22(14-16-24)17-19-31-20-23-11-4-5-12-25(23)26(33)32-18-7-6-10-21-8-2-1-3-9-21/h1-5,8-9,11-16,31H,6-7,10,17-20H2,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line				Bioorg Med Chem Lett 14: 545-8 (2003) BindingDB Entry DOI: 10.7270/Q2M9083Z
					More data for this Ligand-Target Pair