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SMILES: COc1ccc(CCNCc2ccccc2C(=O)NCCCCc2ccccc2)cc1

InChI Key: InChIKey=XPEYHYAMWSPOJP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138567   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 2


(Homo sapiens (Human))		BDBM50138567
PNG
(2-{[2-(4-Methoxy-phenyl)-ethylamino]-methyl}-N-(4-...)
Show SMILES COc1ccc(CCNCc2ccccc2C(=O)NCCCCc2ccccc2)cc1
Show InChI InChI=1S/C27H32N2O2/c1-31-25-16-14-23(15-17-25)18-20-28-21-24-12-5-6-13-26(24)27(30)29-19-8-7-11-22-9-3-2-4-10-22/h2-6,9-10,12-17,28H,7-8,11,18-21H2,1H3,(H,29,30)
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PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line

Bioorg Med Chem Lett 14: 545-8 (2003)


BindingDB Entry DOI: 10.7270/Q2M9083Z
More data for this
Ligand-Target Pair