BDBM50138577 2-{[3-(4-Hydroxy-phenyl)-propylamino]-methyl}-N-(4-phenyl-butyl)-benzamide::CHEMBL150836

SMILES: Oc1ccc(CCCNCc2ccccc2C(=O)NCCCCc2ccccc2)cc1

InChI Key: InChIKey=RKSIDDXPVSIRCB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 2 (Homo sapiens (Human))	BDBM50138577 (2-{[3-(4-Hydroxy-phenyl)-propylamino]-methyl}-N-(4...) Show SMILES Oc1ccc(CCCNCc2ccccc2C(=O)NCCCCc2ccccc2)cc1 Show InChI InChI=1S/C27H32N2O2/c30-25-17-15-23(16-18-25)12-8-19-28-21-24-13-4-5-14-26(24)27(31)29-20-7-6-11-22-9-2-1-3-10-22/h1-5,9-10,13-18,28,30H,6-8,11-12,19-21H2,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line				Bioorg Med Chem Lett 14: 545-8 (2003) BindingDB Entry DOI: 10.7270/Q2M9083Z
					More data for this Ligand-Target Pair