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SMILES: Oc1ccc2CCCC(NCc3ccccc3C(=O)NCCCCc3ccccc3)c2c1

InChI Key: InChIKey=WAXRDAZDTSDCJJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138581   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 2


(Homo sapiens (Human))		BDBM50138581
PNG
(2-[(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-1-ylam...)
Show SMILES Oc1ccc2CCCC(NCc3ccccc3C(=O)NCCCCc3ccccc3)c2c1
Show InChI InChI=1S/C28H32N2O2/c31-24-17-16-22-13-8-15-27(26(22)19-24)30-20-23-12-4-5-14-25(23)28(32)29-18-7-6-11-21-9-2-1-3-10-21/h1-5,9-10,12,14,16-17,19,27,30-31H,6-8,11,13,15,18,20H2,(H,29,32)
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Similars
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line

Bioorg Med Chem Lett 14: 545-8 (2003)


BindingDB Entry DOI: 10.7270/Q2M9083Z
More data for this
Ligand-Target Pair