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SMILES: Nc1ccc(CCNCc2ccccc2C(=O)NCCCCc2ccccc2)cc1

InChI Key: InChIKey=CIERSNQRXNFDSH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138582   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 2


(Homo sapiens (Human))		BDBM50138582
PNG
(2-{[2-(4-Amino-phenyl)-ethylamino]-methyl}-N-(4-ph...)
Show SMILES Nc1ccc(CCNCc2ccccc2C(=O)NCCCCc2ccccc2)cc1
Show InChI InChI=1S/C26H31N3O/c27-24-15-13-22(14-16-24)17-19-28-20-23-11-4-5-12-25(23)26(30)29-18-7-6-10-21-8-2-1-3-9-21/h1-5,8-9,11-16,28H,6-7,10,17-20,27H2,(H,29,30)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line

Bioorg Med Chem Lett 14: 545-8 (2003)


BindingDB Entry DOI: 10.7270/Q2M9083Z
More data for this
Ligand-Target Pair