BDBM50138758 3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[1,2,4]triazole-1-carboxylic acid methyl-phenyl-amide::3-(4-chlorophenyl)-5-(cyclopropylmethylthio)-N-methyl-N-phenyl-1H-1,2,4-triazole-1-carboxamide::CHEMBL335112

SMILES: CN(C(=O)n1nc(nc1SCC1CC1)-c1ccc(Cl)cc1)c1ccccc1

InChI Key: InChIKey=OZDKPVJHMBQMMC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (HSL) (Rattus norvegicus (Rat))	BDBM50138758 (3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[1...) Show SMILES CN(C(=O)n1nc(nc1SCC1CC1)-c1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C20H19ClN4OS/c1-24(17-5-3-2-4-6-17)20(26)25-19(27-13-14-7-8-14)22-18(23-25)15-9-11-16(21)12-10-15/h2-6,9-12,14H,7-8,13H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09	n/a	n/a	n/a	n/a	n/a	n/a
University of Jordan Curated by ChEMBL					Assay Description Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay				J Med Chem 51: 6478-94 (2008) Article DOI: 10.1021/jm800718k BindingDB Entry DOI: 10.7270/Q23778KJ
					More data for this Ligand-Target Pair
Hormone-sensitive lipase (HSL) (Homo sapiens (Human))	BDBM50138758 (3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[1...) Show SMILES CN(C(=O)n1nc(nc1SCC1CC1)-c1ccc(Cl)cc1)c1ccccc1 Show InChI InChI=1S/C20H19ClN4OS/c1-24(17-5-3-2-4-6-17)20(26)25-19(27-13-14-7-8-14)22-18(23-25)15-9-11-16(21)12-10-15/h2-6,9-12,14H,7-8,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of hormone sensitive lipase (HSL).				J Med Chem 47: 400-10 (2004) Article DOI: 10.1021/jm031004s BindingDB Entry DOI: 10.7270/Q2ZG6RN1
					More data for this Ligand-Target Pair