BDBM50139506 5-[1-(4-Methoxy-benzenesulfonyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole::CHEMBL349675
SMILES: COc1ccc(cc1)S(=O)(=O)N1CCC(=CC1)c1ccc2[nH]cc(CCN3CCCC3)c2c1
InChI Key: InChIKey=DOHYKDWALRWYOK-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50139506 (5-[1-(4-Methoxy-benzenesulfonyl)-1,2,3,6-tetrahydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated at the cloned human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 14: 727-9 (2004) BindingDB Entry DOI: 10.7270/Q2M32V5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50139506 (5-[1-(4-Methoxy-benzenesulfonyl)-1,2,3,6-tetrahydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated at the cloned human 5-hydroxytryptamine 1B receptor | Bioorg Med Chem Lett 14: 727-9 (2004) BindingDB Entry DOI: 10.7270/Q2M32V5K | |||||||||||
More data for this Ligand-Target Pair |