BDBM50139520 4-Chloro-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indol-5-yl]-3,6-dihydro-2H-pyridin-1-yl}-thiobenzamide::CHEMBL351036
SMILES: Clc1ccc(cc1)C(=S)NN1CCC(=CC1)c1ccc2[nH]cc(CCN3CCCC3)c2c1
InChI Key: InChIKey=AXEVTXYFZSFYFE-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50139520![]() (4-Chloro-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated at the cloned human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 14: 727-9 (2004) BindingDB Entry DOI: 10.7270/Q2M32V5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50139520![]() (4-Chloro-N-{4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated at the cloned human 5-hydroxytryptamine 1B receptor | Bioorg Med Chem Lett 14: 727-9 (2004) BindingDB Entry DOI: 10.7270/Q2M32V5K | |||||||||||
More data for this Ligand-Target Pair |