BDBM50139704 3-(2,4-Difluoro-phenyl)-4-nitro-5-trifluoromethyl-1H-pyrazole::CHEMBL169038

SMILES: [O-][N+](=O)c1c(n[nH]c1C(F)(F)F)-c1ccc(F)cc1F

InChI Key: InChIKey=MWWONINORNOFIX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1 (Homo sapiens (Human))	BDBM50139704 (3-(2,4-Difluoro-phenyl)-4-nitro-5-trifluoromethyl-...) Show SMILES [O-][N+](=O)c1c(n[nH]c1C(F)(F)F)-c1ccc(F)cc1F Show InChI InChI=1S/C10H4F5N3O2/c11-4-1-2-5(6(12)3-4)7-8(18(19)20)9(17-16-7)10(13,14)15/h1-3H,(H,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Maximum activation of human KATP (SUR1/Kir6.2) channel expressed in Xenopus oocytes				Bioorg Med Chem Lett 14: 813-6 (2004) BindingDB Entry DOI: 10.7270/Q29P312R
					More data for this Ligand-Target Pair