BDBM50139930 CHEMBL269230::N,N'-Dihydroxy-2-(1-methyl-4-phenylacetyl-1H-pyrrol-2-ylmethylene)-malonamide

SMILES: [#6]-n1cc(cc1\[#6]=[#6](\[#6](=O)-[#7]-[#8])-[#6](=O)-[#7]-[#8])-[#6](=O)-[#6]-c1ccccc1

InChI Key: InChIKey=KNABBMZWRHWVHI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2b (Zea mays)	BDBM50139930 (CHEMBL269230 | N,N'-Dihydroxy-2-(1-methyl-4-phenyl...) Show SMILES [#6]-n1cc(cc1\[#6]=[#6](\[#6](=O)-[#7]-[#8])-[#6](=O)-[#7]-[#8])-[#6](=O)-[#6]-c1ccccc1 Show InChI InChI=1S/C17H17N3O5/c1-20-10-12(15(21)7-11-5-3-2-4-6-11)8-13(20)9-14(16(22)18-24)17(23)19-25/h2-6,8-10,24-25H,7H2,1H3,(H,18,22)(H,19,23)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50139930 (CHEMBL269230 | N,N'-Dihydroxy-2-(1-methyl-4-phenyl...) Show SMILES [#6]-n1cc(cc1\[#6]=[#6](\[#6](=O)-[#7]-[#8])-[#6](=O)-[#7]-[#8])-[#6](=O)-[#6]-c1ccccc1 Show InChI InChI=1S/C17H17N3O5/c1-20-10-12(15(21)7-11-5-3-2-4-6-11)8-13(20)9-14(16(22)18-24)17(23)19-25/h2-6,8-10,24-25H,7H2,1H3,(H,18,22)(H,19,23)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair