BDBM50139932 CHEMBL13000::N-Hydroxy-2-methyl-3-(1-methyl-4-phenylacetyl-1H-pyrrol-2-yl)-acrylamide

SMILES: CC(=Cc1cc(cn1C)C(=O)Cc1ccccc1)C(=O)NO

InChI Key: InChIKey=ARRLTHBEMWDSBH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD2 (Zea mays)	BDBM50139932 (CHEMBL13000 | N-Hydroxy-2-methyl-3-(1-methyl-4-phe...) Show SMILES CC(=Cc1cc(cn1C)C(=O)Cc1ccccc1)C(=O)NO |w:2.2| Show InChI InChI=1S/C17H18N2O3/c1-12(17(21)18-22)8-15-10-14(11-19(15)2)16(20)9-13-6-4-3-5-7-13/h3-8,10-11,22H,9H2,1-2H3,(H,18,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50139932 (CHEMBL13000 | N-Hydroxy-2-methyl-3-(1-methyl-4-phe...) Show SMILES CC(=Cc1cc(cn1C)C(=O)Cc1ccccc1)C(=O)NO |w:2.2| Show InChI InChI=1S/C17H18N2O3/c1-12(17(21)18-22)8-15-10-14(11-19(15)2)16(20)9-13-6-4-3-5-7-13/h3-8,10-11,22H,9H2,1-2H3,(H,18,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair