BDBM50139939 CHEMBL276707::N-Hydroxy-3-[1-methyl-4-(2-phenyl-cyclopropanecarbonyl)-1H-pyrrol-2-yl]-acrylamide

SMILES: Cn1cc(cc1C=CC(=O)NO)C(=O)C1CC1c1ccccc1

InChI Key: InChIKey=RLJXQVYXDDGCDN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD2 (Zea mays)	BDBM50139939 (CHEMBL276707 | N-Hydroxy-3-[1-methyl-4-(2-phenyl-c...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)C1CC1c1ccccc1 |w:7.8| Show InChI InChI=1S/C18H18N2O3/c1-20-11-13(9-14(20)7-8-17(21)19-23)18(22)16-10-15(16)12-5-3-2-4-6-12/h2-9,11,15-16,23H,10H2,1H3,(H,19,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50139939 (CHEMBL276707 | N-Hydroxy-3-[1-methyl-4-(2-phenyl-c...) Show SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)C1CC1c1ccccc1 |w:7.8| Show InChI InChI=1S/C18H18N2O3/c1-20-11-13(9-14(20)7-8-17(21)19-23)18(22)16-10-15(16)12-5-3-2-4-6-12/h2-9,11,15-16,23H,10H2,1H3,(H,19,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	309	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair