BDBM50139944 CHEMBL12890::N-Hydroxy-3-[1-methyl-4-(naphthalene-1-carbonyl)-1H-pyrrol-2-yl]-acrylamide

SMILES: Cn1cc(cc1\C=C\C(=O)NO)C(=O)c1cccc2ccccc12

InChI Key: InChIKey=SATKHECYBIEDEL-MDZDMXLPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD2 (Zea mays)	BDBM50139944 (CHEMBL12890 | N-Hydroxy-3-[1-methyl-4-(naphthalene...) Show SMILES Cn1cc(cc1\C=C\C(=O)NO)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C19H16N2O3/c1-21-12-14(11-15(21)9-10-18(22)20-24)19(23)17-8-4-6-13-5-2-3-7-16(13)17/h2-12,24H,1H3,(H,20,22)/b10-9+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Concentration required for inhibition of histone deacetylase HD2 in vitro.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50139944 (CHEMBL12890 | N-Hydroxy-3-[1-methyl-4-(naphthalene...) Show SMILES Cn1cc(cc1\C=C\C(=O)NO)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C19H16N2O3/c1-21-12-14(11-15(21)9-10-18(22)20-24)19(23)17-8-4-6-13-5-2-3-7-16(13)17/h2-12,24H,1H3,(H,20,22)/b10-9+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory concentration against histone deacetylase HD2 enzyme.				J Med Chem 47: 1098-109 (2004) Checked by Author Article DOI: 10.1021/jm030990+ BindingDB Entry DOI: 10.7270/Q24X5773
					More data for this Ligand-Target Pair