BDBM50140245 CHEMBL3759574

SMILES: N#Cc1ccc(cc1)-c1cc(OCC2CCNCC2)cnc1-c1ccsc1

InChI Key: InChIKey=IVJJCXGJRKNJJJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50140245 (CHEMBL3759574) Show SMILES N#Cc1ccc(cc1)-c1cc(OCC2CCNCC2)cnc1-c1ccsc1 Show InChI InChI=1S/C22H21N3OS/c23-12-16-1-3-18(4-2-16)21-11-20(26-14-17-5-8-24-9-6-17)13-25-22(21)19-7-10-27-15-19/h1-4,7,10-11,13,15,17,24H,5-6,8-9,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair