null

SMILES: C[C@@H](C(O)=O)c1ccc(C[C@H]2CCC[C@@H]2O)cc1

InChI Key: InChIKey=SHAHPWSYJFYMRX-HONMWMINSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50140317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50140317 ((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...) Show SMILES C[C@@H](C(O)=O)c1ccc(C[C@H]2CCC[C@@H]2O)cc1 Show InChI InChI=1S/C15H20O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13-14,16H,2-4,9H2,1H3,(H,17,18)/t10-,13-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory potency against Prostaglandin G/H synthase 1 in human whole blood assay				Bioorg Med Chem Lett 14: 1201-3 (2004) Article DOI: 10.1016/j.bmcl.2003.12.047 BindingDB Entry DOI: 10.7270/Q27P8XTN
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50140317 ((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...) Show SMILES C[C@@H](C(O)=O)c1ccc(C[C@H]2CCC[C@@H]2O)cc1 Show InChI InChI=1S/C15H20O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13-14,16H,2-4,9H2,1H3,(H,17,18)/t10-,13-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIA				Bioorg Med Chem 19: 3299-311 (2011) Article DOI: 10.1016/j.bmc.2011.04.050 BindingDB Entry DOI: 10.7270/Q2NZ881Z
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50140317 ((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...) Show SMILES C[C@@H](C(O)=O)c1ccc(C[C@H]2CCC[C@@H]2O)cc1 Show InChI InChI=1S/C15H20O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13-14,16H,2-4,9H2,1H3,(H,17,18)/t10-,13-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human prostaglandin G/H synthase 1				Bioorg Med Chem Lett 14: 1201-3 (2004) Article DOI: 10.1016/j.bmcl.2003.12.047 BindingDB Entry DOI: 10.7270/Q27P8XTN
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50140317 ((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...) Show SMILES C[C@@H](C(O)=O)c1ccc(C[C@H]2CCC[C@@H]2O)cc1 Show InChI InChI=1S/C15H20O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13-14,16H,2-4,9H2,1H3,(H,17,18)/t10-,13-,14+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of human whole blood COX-2 assessed as production of PGE2 after 24 hrs by EIA				Bioorg Med Chem 19: 3299-311 (2011) Article DOI: 10.1016/j.bmc.2011.04.050 BindingDB Entry DOI: 10.7270/Q2NZ881Z
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50140317 ((R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phe...) Show SMILES C[C@@H](C(O)=O)c1ccc(C[C@H]2CCC[C@@H]2O)cc1 Show InChI InChI=1S/C15H20O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13-14,16H,2-4,9H2,1H3,(H,17,18)/t10-,13-,14+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Prostaglandin G/H synthase 2				Bioorg Med Chem Lett 14: 1201-3 (2004) Article DOI: 10.1016/j.bmcl.2003.12.047 BindingDB Entry DOI: 10.7270/Q27P8XTN
					More data for this Ligand-Target Pair