null

SMILES: CCN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(C(=O)OC)n(Cc3ccc(OC)cc3)c2C1=O

InChI Key: InChIKey=PKJTVYVQDCERGJ-CVEARBPZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50140612 (CHEMBL285573 | methyl 5-ethyl-3-(4-methoxybenzyl)-...) Show SMILES CCN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(C(=O)OC)n(Cc3ccc(OC)cc3)c2C1=O |r,t:3| Show InChI InChI=1S/C22H25N5O4/c1-4-25-20(28)17-18(27-16-7-5-6-15(16)23-22(25)27)24-19(21(29)31-3)26(17)12-13-8-10-14(30-2)11-9-13/h8-11,15-16H,4-7,12H2,1-3H3/t15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Lavras-UFLA Curated by ChEMBL					Assay Description Inhibition of PDE5				Eur J Med Chem 43: 1632-8 (2008) Article DOI: 10.1016/j.ejmech.2007.10.019 BindingDB Entry DOI: 10.7270/Q2Q81F9P
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50140612 (CHEMBL285573 | methyl 5-ethyl-3-(4-methoxybenzyl)-...) Show SMILES CCN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(C(=O)OC)n(Cc3ccc(OC)cc3)c2C1=O |r,t:3| Show InChI InChI=1S/C22H25N5O4/c1-4-25-20(28)17-18(27-16-7-5-6-15(16)23-22(25)27)24-19(21(29)31-3)26(17)12-13-8-10-14(30-2)11-9-13/h8-11,15-16H,4-7,12H2,1-3H3/t15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against human phosphodiesterase 5 (PDE5) enzyme				Bioorg Med Chem Lett 14: 1291-4 (2004) Article DOI: 10.1016/j.bmcl.2003.12.027 BindingDB Entry DOI: 10.7270/Q2BG2NF0
					More data for this Ligand-Target Pair