BDBM50140773 2-Bromomethyl-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide::CHEMBL281797

SMILES: FC(F)(F)c1cc(CNC(=O)c2c(CBr)nc3ccccc3c2-c2ccccc2)cc(c1)C(F)(F)F

InChI Key: InChIKey=UIBQKGCCXYTNSB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 1 receptor (Homo sapiens (Human))	BDBM50140773 (2-Bromomethyl-4-phenyl-quinoline-3-carboxylic acid...) Show SMILES FC(F)(F)c1cc(CNC(=O)c2c(CBr)nc3ccccc3c2-c2ccccc2)cc(c1)C(F)(F)F Show InChI InChI=1S/C26H17BrF6N2O/c27-13-21-23(22(16-6-2-1-3-7-16)19-8-4-5-9-20(19)35-21)24(36)34-14-15-10-17(25(28,29)30)12-18(11-15)26(31,32)33/h1-12H,13-14H2,(H,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0100	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells using [125I]- SP radioligand				J Med Chem 47: 1315-8 (2004) Article DOI: 10.1021/jm034219a BindingDB Entry DOI: 10.7270/Q2F76C0W
					More data for this Ligand-Target Pair