BDBM50142075 CHEMBL3758747

SMILES: N#Cc1ccc(cc1)-c1cc(OCC2CCNCC2)cnc1-c1cccnc1

InChI Key: InChIKey=YWSQKQUADQEORE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50142075 (CHEMBL3758747) Show SMILES N#Cc1ccc(cc1)-c1cc(OCC2CCNCC2)cnc1-c1cccnc1 Show InChI InChI=1S/C23H22N4O/c24-13-17-3-5-19(6-4-17)22-12-21(28-16-18-7-10-25-11-8-18)15-27-23(22)20-2-1-9-26-14-20/h1-6,9,12,14-15,18,25H,7-8,10-11,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair