BDBM50142165 2-[4-(N'-Acetyl-hydrazinomethyl)-benzoylamino]-5-chloro-N-(5-chloro-pyridin-2-yl)-benzamide::CHEMBL368914

SMILES: CC(=O)NNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=KTYNKAIXVXBDAA-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50142165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin-1 (Homo sapiens (Human))	BDBM50142165 (2-[4-(N'-Acetyl-hydrazinomethyl)-benzoylamino]-5-c...) Show SMILES CC(=O)NNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O3/c1-13(30)29-26-11-14-2-4-15(5-3-14)21(31)27-19-8-6-16(23)10-18(19)22(32)28-20-9-7-17(24)12-25-20/h2-10,12,26H,11H2,1H3,(H,27,31)(H,29,30)(H,25,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against trypsin.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM50142165 (2-[4-(N'-Acetyl-hydrazinomethyl)-benzoylamino]-5-c...) Show SMILES CC(=O)NNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O3/c1-13(30)29-26-11-14-2-4-15(5-3-14)21(31)27-19-8-6-16(23)10-18(19)22(32)28-20-9-7-17(24)12-25-20/h2-10,12,26H,11H2,1H3,(H,27,31)(H,29,30)(H,25,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against activated protein C				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50142165 (2-[4-(N'-Acetyl-hydrazinomethyl)-benzoylamino]-5-c...) Show SMILES CC(=O)NNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O3/c1-13(30)29-26-11-14-2-4-15(5-3-14)21(31)27-19-8-6-16(23)10-18(19)22(32)28-20-9-7-17(24)12-25-20/h2-10,12,26H,11H2,1H3,(H,27,31)(H,29,30)(H,25,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against tissue type plasminogen activator.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50142165 (2-[4-(N'-Acetyl-hydrazinomethyl)-benzoylamino]-5-c...) Show SMILES CC(=O)NNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O3/c1-13(30)29-26-11-14-2-4-15(5-3-14)21(31)27-19-8-6-16(23)10-18(19)22(32)28-20-9-7-17(24)12-25-20/h2-10,12,26H,11H2,1H3,(H,27,31)(H,29,30)(H,25,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor X.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50142165 (2-[4-(N'-Acetyl-hydrazinomethyl)-benzoylamino]-5-c...) Show SMILES CC(=O)NNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O3/c1-13(30)29-26-11-14-2-4-15(5-3-14)21(31)27-19-8-6-16(23)10-18(19)22(32)28-20-9-7-17(24)12-25-20/h2-10,12,26H,11H2,1H3,(H,27,31)(H,29,30)(H,25,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against plasmin.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50142165 (2-[4-(N'-Acetyl-hydrazinomethyl)-benzoylamino]-5-c...) Show SMILES CC(=O)NNCc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O3/c1-13(30)29-26-11-14-2-4-15(5-3-14)21(31)27-19-8-6-16(23)10-18(19)22(32)28-20-9-7-17(24)12-25-20/h2-10,12,26H,11H2,1H3,(H,27,31)(H,29,30)(H,25,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against thrombin.				Bioorg Med Chem Lett 14: 989-93 (2004) Article DOI: 10.1016/j.bmcl.2003.11.080 BindingDB Entry DOI: 10.7270/Q2X34WXD
					More data for this Ligand-Target Pair