BDBM50142234 CHEMBL3758402

SMILES: CCNCc1ccc(cc1)-c1cc(OCC2CCNCC2)cnc1-c1ccc(C)cc1

InChI Key: InChIKey=ASBGZWKSHORKFW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50142234 (CHEMBL3758402) Show SMILES CCNCc1ccc(cc1)-c1cc(OCC2CCNCC2)cnc1-c1ccc(C)cc1 Show InChI InChI=1S/C27H33N3O/c1-3-28-17-21-6-10-23(11-7-21)26-16-25(31-19-22-12-14-29-15-13-22)18-30-27(26)24-8-4-20(2)5-9-24/h4-11,16,18,22,28-29H,3,12-15,17,19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair