BDBM50142247 CHEMBL3759745

SMILES: C(Oc1cnc(-c2ccccc2)c(c1)-c1ccccc1)C1CCNCC1

InChI Key: InChIKey=JQTVRZZEJIEHGP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50142247 (CHEMBL3759745) Show SMILES C(Oc1cnc(-c2ccccc2)c(c1)-c1ccccc1)C1CCNCC1 Show InChI InChI=1S/C23H24N2O/c1-3-7-19(8-4-1)22-15-21(26-17-18-11-13-24-14-12-18)16-25-23(22)20-9-5-2-6-10-20/h1-10,15-16,18,24H,11-14,17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair